G371-0115 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-{2-ethoxy-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-4-yl}acetamide

G371-0115 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-{2-ethoxy-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-4-yl}acetamide
G371-0115 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-{2-ethoxy-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-4-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G371-0115
N-(5-chloro-2,4-dimethoxyphenyl)-2-{2-ethoxy-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-4-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G371-0115

Molecular Formula

C19H19ClN4O5 (C19 H19 ClN4 O5)

Compound Name

N-(5-chloro-2,4-dimethoxyphenyl)-2-{2-ethoxy-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-4-yl}acetamide

IUPAC name

N-(5-chloro-24-dimethoxyphenyl)-2-{2-ethoxy-3-oxo-3H4H-pyrido[23-b]pyrazin-4-yl}acetamide

SMILES

CCOC1=Nc2cccnc2N(CC(Nc(c(OC)c2)cc(Cl)c2OC)=O)C1=O

InChI

InChI=1S/C19H19ClN4O5/c1-4-29-18-19(26)24(17-12(23-18)6-5-7-21-17)10-16(25)22-13-8-11(20)14(27-2)9-15(13)28-3/h5-9H,4,10H2,1-3H3,(H,22,25)

InChI Key

ODOSEXCFMNHVKJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15005083

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.84

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.217

Distribution Coefficient, logD

2.209

Water Solubility, LogSw

-3.17

Polar Surface Area

79.645

Acid Dissociation Constant (pKa)

9.12

Base Dissociation Constant (pKb)

0.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

G371-0115 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G371-0115 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G371-0115?
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What is the minimum amount of G371-0115 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G371-0115
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G371-0115
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G371-0115 available by request