G373-0279 Screening compound: 4-{4-[(2,3-dihydro-1H-indol-1-yl)methyl]-5-methyl-1,3-oxazol-2-yl}-N-[4-(propan-2-yl)phenyl]benzamide

G373-0279 Screening compound: 4-{4-[(2,3-dihydro-1H-indol-1-yl)methyl]-5-methyl-1,3-oxazol-2-yl}-N-[4-(propan-2-yl)phenyl]benzamide
G373-0279 Screening compound: 4-{4-[(2,3-dihydro-1H-indol-1-yl)methyl]-5-methyl-1,3-oxazol-2-yl}-N-[4-(propan-2-yl)phenyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-0279
4-{4-[(2,3-dihydro-1H-indol-1-yl)methyl]-5-methyl-1,3-oxazol-2-yl}-N-[4-(propan-2-yl)phenyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-0279

Molecular Formula

C29H29N3O2 (C29 H29 N3 O2)

Compound Name

4-{4-[(2,3-dihydro-1H-indol-1-yl)methyl]-5-methyl-1,3-oxazol-2-yl}-N-[4-(propan-2-yl)phenyl]benzamide

IUPAC name

4-{4-[(23-dihydro-1H-indol-1-yl)methyl]-5-methyl-13-oxazol-2-yl}-N-[4-(propan-2-yl)phenyl]benzamide

SMILES

CC(C)c(cc1)ccc1NC(c(cc1)ccc1-c1nc(CN(CC2)c3c2cccc3)c(C)o1)=O

InChI

InChI=1S/C29H29N3O2/c1-19(2)21-12-14-25(15-13-21)30-28(33)23-8-10-24(11-9-23)29-31-26(20(3)34-29)18-32-17-16-22-6-4-5-7-27(22)32/h4-15,19H,16-18H2,1-3H3,(H,30,33)

InChI Key

GAPOQPPGXCLOFP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15005229

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.57

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.368

Distribution Coefficient, logD

6.368

Water Solubility, LogSw

-5.59

Polar Surface Area

44.380

Acid Dissociation Constant (pKa)

11.17

Base Dissociation Constant (pKb)

1.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.10

G373-0279 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G373-0279 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-0279?
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What is the minimum amount of G373-0279 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-0279
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-0279
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-0279 available by request