G373-0546 Screening compound: 4-chloro-N-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}benzene-1-sulfonamide

G373-0546 Screening compound: 4-chloro-N-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}benzene-1-sulfonamide
G373-0546 Screening compound: 4-chloro-N-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-0546
4-chloro-N-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-0546

Molecular Formula

C18H17ClN2O4S (C18 H17 ClN2 O4 S)

Compound Name

4-chloro-N-{[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}benzene-1-sulfonamide

IUPAC name

4-chloro-N-{[2-(4-methoxyphenyl)-5-methyl-13-oxazol-4-yl]methyl}benzene-1-sulfonamide

SMILES

Cc1c(CNS(c(cc2)ccc2Cl)(=O)=O)nc(-c(cc2)ccc2OC)o1

InChI

InChI=1S/C18H17ClN2O4S/c1-12-17(11-20-26(22,23)16-9-5-14(19)6-10-16)21-18(25-12)13-3-7-15(24-2)8-4-13/h3-10,20H,11H2,1-2H3

InChI Key

LBCTUBACRNPQQD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15005331

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.86

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.093

Distribution Coefficient, logD

4.086

Water Solubility, LogSw

-4.61

Polar Surface Area

67.663

Acid Dissociation Constant (pKa)

9.18

Base Dissociation Constant (pKb)

0.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

G373-0546 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G373-0546 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-0546?
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What is the minimum amount of G373-0546 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-0546
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-0546
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-0546 available by request