G373-0873 Screening compound: N-(2,5-dimethylphenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide

G373-0873 Screening compound: N-(2,5-dimethylphenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide
G373-0873 Screening compound: N-(2,5-dimethylphenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-0873
N-(2,5-dimethylphenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-0873

Molecular Formula

C24H29N5O3 (C24 H29 N5 O3)

Compound Name

N-(2,5-dimethylphenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide

IUPAC name

N-(25-dimethylphenyl)-4-{23-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide

SMILES

Cc1cc(NC(N(CC2)CCC2N(CCN(Cc2ncccc2)C2=O)C2=O)=O)c(C)cc1

InChI

InChI=1S/C24H29N5O3/c1-17-6-7-18(2)21(15-17)26-24(32)27-11-8-20(9-12-27)29-14-13-28(22(30)23(29)31)16-19-5-3-4-10-25-19/h3-7,10,15,20H,8-9,11-14,16H2,1-2H3,(H,26,32)

InChI Key

VITWZKKFEKXWMR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15005542

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.954

Distribution Coefficient, logD

1.954

Water Solubility, LogSw

-2.52

Polar Surface Area

66.793

Acid Dissociation Constant (pKa)

13.97

Base Dissociation Constant (pKb)

2.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

G373-0873 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G373-0873 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-0873?
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What is the minimum amount of G373-0873 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-0873
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-0873
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-0873 available by request