G373-1028 Screening compound: N-(2-chlorophenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide

G373-1028 Screening compound: N-(2-chlorophenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide
G373-1028 Screening compound: N-(2-chlorophenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-1028
N-(2-chlorophenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-1028

Molecular Formula

C22H24ClN5O3 (C22 H24 ClN5 O3)

Compound Name

N-(2-chlorophenyl)-4-{2,3-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide

IUPAC name

N-(2-chlorophenyl)-4-{23-dioxo-4-[(pyridin-2-yl)methyl]piperazin-1-yl}piperidine-1-carboxamide

SMILES

O=C(Nc(cccc1)c1Cl)N(CC1)CCC1N(CCN(Cc1ncccc1)C1=O)C1=O

InChI

InChI=1S/C22H24ClN5O3/c23-18-6-1-2-7-19(18)25-22(31)26-11-8-17(9-12-26)28-14-13-27(20(29)21(28)30)15-16-5-3-4-10-24-16/h1-7,10,17H,8-9,11-15H2,(H,25,31)

InChI Key

NYRYCJORGHKMBQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15005653

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.92

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.963

Distribution Coefficient, logD

1.963

Water Solubility, LogSw

-2.52

Polar Surface Area

66.793

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

2.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G373-1028 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Anti-HIV1 Library (19540 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G373-1028 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-1028?
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What is the minimum amount of G373-1028 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-1028
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-1028
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-1028 available by request