G373-2058 Screening compound: 1-(2,3-dihydro-1,4-benzodioxine-6-sulfonyl)-4-{3H-imidazo[4,5-b]pyridin-3-yl}piperidine

G373-2058 Screening compound: 1-(2,3-dihydro-1,4-benzodioxine-6-sulfonyl)-4-{3H-imidazo[4,5-b]pyridin-3-yl}piperidine
G373-2058 Screening compound: 1-(2,3-dihydro-1,4-benzodioxine-6-sulfonyl)-4-{3H-imidazo[4,5-b]pyridin-3-yl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-2058
1-(2,3-dihydro-1,4-benzodioxine-6-sulfonyl)-4-{3H-imidazo[4,5-b]pyridin-3-yl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-2058

Molecular Formula

C19H20N4O4S (C19 H20 N4 O4 S)

Compound Name

1-(2,3-dihydro-1,4-benzodioxine-6-sulfonyl)-4-{3H-imidazo[4,5-b]pyridin-3-yl}piperidine

IUPAC name

1-(23-dihydro-14-benzodioxine-6-sulfonyl)-4-{3H-imidazo[45-b]pyridin-3-yl}piperidine

SMILES

O=S(c(cc1)cc2c1OCCO2)(N(CC1)CCC1n1c2ncccc2nc1)=O

InChI

InChI=1S/C19H20N4O4S/c24-28(25,15-3-4-17-18(12-15)27-11-10-26-17)22-8-5-14(6-9-22)23-13-21-16-2-1-7-20-19(16)23/h1-4,7,12-14H,5-6,8-11H2

InChI Key

DQNVROQPOAONEP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11683123

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.46

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.317

Distribution Coefficient, logD

1.317

Water Solubility, LogSw

-2.21

Polar Surface Area

67.964

Acid Dissociation Constant (pKa)

19.15

Base Dissociation Constant (pKb)

2.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

G373-2058 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G373-2058 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-2058?
Check Price and Availability of G373-2058, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-2058 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-2058
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-2058
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-2058 available by request