G373-2380 Screening compound: 4-acetamido-N-{3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}benzamide

G373-2380 Screening compound: 4-acetamido-N-{3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}benzamide
G373-2380 Screening compound: 4-acetamido-N-{3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-2380
4-acetamido-N-{3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-2380

Molecular Formula

C25H25N5O2 (C25 H25 N5 O2)

Compound Name

4-acetamido-N-{3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}benzamide

IUPAC name

4-acetamido-N-{3-[2-(4-methylphenyl)-3H-imidazo[45-b]pyridin-3-yl]propyl}benzamide

SMILES

CC(Nc(cc1)ccc1C(NCCCn1c(-c2ccc(C)cc2)nc2cccnc12)=O)=O

InChI

InChI=1S/C25H25N5O2/c1-17-6-8-19(9-7-17)23-29-22-5-3-14-26-24(22)30(23)16-4-15-27-25(32)20-10-12-21(13-11-20)28-18(2)31/h3,5-14H,4,15-16H2,1-2H3,(H,27,32)(H,28,31)

InChI Key

APZJJCXEGORPGQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137667

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.315

Distribution Coefficient, logD

3.315

Water Solubility, LogSw

-3.40

Polar Surface Area

67.569

Acid Dissociation Constant (pKa)

10.78

Base Dissociation Constant (pKb)

3.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G373-2380 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Proteases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with G373-2380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-2380?
Check Price and Availability of G373-2380, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-2380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-2380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-2380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-2380 available by request