G373-2741 Screening compound: methyl 4-methyl-2-[(4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carbonyl)amino]benzoate

G373-2741 Screening compound: methyl 4-methyl-2-[(4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carbonyl)amino]benzoate
G373-2741 Screening compound: methyl 4-methyl-2-[(4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carbonyl)amino]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-2741
methyl 4-methyl-2-[(4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carbonyl)amino]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-2741

Molecular Formula

C27H32N4O5 (C27 H32 N4 O5)

Compound Name

methyl 4-methyl-2-[(4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carbonyl)amino]benzoate

IUPAC name

methyl 4-methyl-2-[(4-{4-[(4-methylphenyl)methyl]-23-dioxopiperazin-1-yl}piperidine-1-carbonyl)amino]benzoate

SMILES

Cc1ccc(CN(CCN(C(CC2)CCN2C(Nc(cc(C)cc2)c2C(OC)=O)=O)C2=O)C2=O)cc1

InChI

InChI=1S/C27H32N4O5/c1-18-4-7-20(8-5-18)17-30-14-15-31(25(33)24(30)32)21-10-12-29(13-11-21)27(35)28-23-16-19(2)6-9-22(23)26(34)36-3/h4-9,16,21H,10-15,17H2,1-3H3,(H,28,35)

InChI Key

IFNSWIONPTWCBJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137745

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.162

Distribution Coefficient, logD

3.161

Water Solubility, LogSw

-3.19

Polar Surface Area

78.424

Acid Dissociation Constant (pKa)

10.30

Base Dissociation Constant (pKb)

1.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.70

G373-2741 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with G373-2741 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-2741?
Check Price and Availability of G373-2741, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-2741 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-2741
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-2741
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-2741 available by request