G373-2742 Screening compound: N-(2,5-dichlorophenyl)-4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carboxamide

G373-2742 Screening compound: N-(2,5-dichlorophenyl)-4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carboxamide
G373-2742 Screening compound: N-(2,5-dichlorophenyl)-4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-2742
N-(2,5-dichlorophenyl)-4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-2742

Molecular Formula

C24H26Cl2N4O3 (C24 H26 Cl2 N4 O3)

Compound Name

N-(2,5-dichlorophenyl)-4-{4-[(4-methylphenyl)methyl]-2,3-dioxopiperazin-1-yl}piperidine-1-carboxamide

IUPAC name

N-(25-dichlorophenyl)-4-{4-[(4-methylphenyl)methyl]-23-dioxopiperazin-1-yl}piperidine-1-carboxamide

SMILES

Cc1ccc(CN(CCN(C(CC2)CCN2C(Nc(cc(cc2)Cl)c2Cl)=O)C2=O)C2=O)cc1

InChI

InChI=1S/C24H26Cl2N4O3/c1-16-2-4-17(5-3-16)15-29-12-13-30(23(32)22(29)31)19-8-10-28(11-9-19)24(33)27-21-14-18(25)6-7-20(21)26/h2-7,14,19H,8-13,15H2,1H3,(H,27,33)

InChI Key

SPNFQEJNKQJDKW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137746

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.216

Distribution Coefficient, logD

4.216

Water Solubility, LogSw

-4.39

Polar Surface Area

57.250

Acid Dissociation Constant (pKa)

10.26

Base Dissociation Constant (pKb)

1.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

G373-2742 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with G373-2742 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-2742?
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What is the minimum amount of G373-2742 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-2742
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-2742
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-2742 available by request