G373-2890 Screening compound: 4-[(dimethylcarbamoyl)methyl]-N-[(4-fluorophenyl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

G373-2890 Screening compound: 4-[(dimethylcarbamoyl)methyl]-N-[(4-fluorophenyl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide
G373-2890 Screening compound: 4-[(dimethylcarbamoyl)methyl]-N-[(4-fluorophenyl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-2890
4-[(dimethylcarbamoyl)methyl]-N-[(4-fluorophenyl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-2890

Molecular Formula

C20H20FN3O4 (C20 H20 FN3 O4)

Compound Name

4-[(dimethylcarbamoyl)methyl]-N-[(4-fluorophenyl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

IUPAC name

4-[(dimethylcarbamoyl)methyl]-N-[(4-fluorophenyl)methyl]-3-oxo-34-dihydro-2H-14-benzoxazine-6-carboxamide

SMILES

CN(C)C(CN1c(cc(cc2)C(NCc(cc3)ccc3F)=O)c2OCC1=O)=O

InChI

InChI=1S/C20H20FN3O4/c1-23(2)18(25)11-24-16-9-14(5-8-17(16)28-12-19(24)26)20(27)22-10-13-3-6-15(21)7-4-13/h3-9H,10-12H2,1-2H3,(H,22,27)

InChI Key

GABWJXHVWQLRNI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137802

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.4

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.557

Distribution Coefficient, logD

0.557

Water Solubility, LogSw

-2.14

Polar Surface Area

64.226

Acid Dissociation Constant (pKa)

12.25

Base Dissociation Constant (pKb)

4.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G373-2890 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Cardiovascular Library (22201 compounds)

STING Agonist Library (5895 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cardiovascular
  • Cancer
  • Immune system
Mechanism of action:
  • Epigenetic
Targets:
  • Others

References: we are preparing a list of scientific research reports with G373-2890 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-2890?
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What is the minimum amount of G373-2890 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-2890
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-2890
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-2890 available by request