G373-2995 Screening compound: N-benzyl-N-methyl-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

G373-2995 Screening compound: N-benzyl-N-methyl-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide
G373-2995 Screening compound: N-benzyl-N-methyl-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-2995
N-benzyl-N-methyl-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-2995

Molecular Formula

C23H25N3O4 (C23 H25 N3 O4)

Compound Name

N-benzyl-N-methyl-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

IUPAC name

N-benzyl-N-methyl-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-34-dihydro-2H-14-benzoxazine-6-carboxamide

SMILES

CN(Cc1ccccc1)C(c(cc1)cc(N2CC(N3CCCC3)=O)c1OCC2=O)=O

InChI

InChI=1S/C23H25N3O4/c1-24(14-17-7-3-2-4-8-17)23(29)18-9-10-20-19(13-18)26(22(28)16-30-20)15-21(27)25-11-5-6-12-25/h2-4,7-10,13H,5-6,11-12,14-16H2,1H3

InChI Key

GLUWWMIVBLCJKM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137861

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.601

Distribution Coefficient, logD

1.601

Water Solubility, LogSw

-2.07

Polar Surface Area

56.977

Acid Dissociation Constant (pKa)

20.50

Base Dissociation Constant (pKb)

-1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

G373-2995 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G373-2995 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-2995?
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What is the minimum amount of G373-2995 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-2995
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-2995
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-2995 available by request