G373-3083 Screening compound: N-(4-fluorophenyl)-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

G373-3083 Screening compound: N-(4-fluorophenyl)-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide
G373-3083 Screening compound: N-(4-fluorophenyl)-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3083
N-(4-fluorophenyl)-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3083

Molecular Formula

C21H20FN3O4 (C21 H20 FN3 O4)

Compound Name

N-(4-fluorophenyl)-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

IUPAC name

N-(4-fluorophenyl)-3-oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-34-dihydro-2H-14-benzoxazine-6-carboxamide

SMILES

O=C(CN1c(cc(cc2)C(Nc(cc3)ccc3F)=O)c2OCC1=O)N1CCCC1

InChI

InChI=1S/C21H20FN3O4/c22-15-4-6-16(7-5-15)23-21(28)14-3-8-18-17(11-14)25(20(27)13-29-18)12-19(26)24-9-1-2-10-24/h3-8,11H,1-2,9-10,12-13H2,(H,23,28)

InChI Key

JRGURMMRPCQBJR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642258

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.825

Distribution Coefficient, logD

1.824

Water Solubility, LogSw

-2.53

Polar Surface Area

63.918

Acid Dissociation Constant (pKa)

10.39

Base Dissociation Constant (pKb)

-1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

G373-3083 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G373-3083 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3083?
Check Price and Availability of G373-3083, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-3083 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3083
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3083
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3083 available by request