G373-3183 Screening compound: 3-chloro-4-methyl-N-{2-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}benzene-1-sulfonamide

G373-3183 Screening compound: 3-chloro-4-methyl-N-{2-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}benzene-1-sulfonamide
G373-3183 Screening compound: 3-chloro-4-methyl-N-{2-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3183
3-chloro-4-methyl-N-{2-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3183

Molecular Formula

C16H14ClF3N4O2S (C16 H14 ClF3 N4 O2 S)

Compound Name

3-chloro-4-methyl-N-{2-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}benzene-1-sulfonamide

IUPAC name

3-chloro-4-methyl-N-{2-[2-(trifluoromethyl)-3H-imidazo[45-b]pyridin-3-yl]ethyl}benzene-1-sulfonamide

SMILES

Cc(ccc(S(NCCn1c2ncccc2nc1C(F)(F)F)(=O)=O)c1)c1Cl

InChI

InChI=1S/C16H14ClF3N4O2S/c1-10-4-5-11(9-12(10)17)27(25,26)22-7-8-24-14-13(3-2-6-21-14)23-15(24)16(18,19)20/h2-6,9,22H,7-8H2,1H3

InChI Key

QGSAZMSBWZBZEH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137948

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.83

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.083

Distribution Coefficient, logD

4.083

Water Solubility, LogSw

-4.29

Polar Surface Area

61.923

Acid Dissociation Constant (pKa)

11.79

Base Dissociation Constant (pKb)

1.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G373-3183 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G373-3183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3183?
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What is the minimum amount of G373-3183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3183 available by request