G373-3305 Screening compound: 1-(3-methoxybenzenesulfonyl)-4-({3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)piperazine

G373-3305 Screening compound: 1-(3-methoxybenzenesulfonyl)-4-({3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)piperazine
G373-3305 Screening compound: 1-(3-methoxybenzenesulfonyl)-4-({3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3305
1-(3-methoxybenzenesulfonyl)-4-({3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3305

Molecular Formula

C24H25N5O3S (C24 H25 N5 O3 S)

Compound Name

1-(3-methoxybenzenesulfonyl)-4-({3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)piperazine

IUPAC name

1-(3-methoxybenzenesulfonyl)-4-({3-phenyl-3H-imidazo[45-b]pyridin-2-yl}methyl)piperazine

SMILES

COc1cccc(S(N2CCN(Cc(n3-c4ccccc4)nc4c3nccc4)CC2)(=O)=O)c1

InChI

InChI=1S/C24H25N5O3S/c1-32-20-9-5-10-21(17-20)33(30,31)28-15-13-27(14-16-28)18-23-26-22-11-6-12-25-24(22)29(23)19-7-3-2-4-8-19/h2-12,17H,13-16,18H2,1H3

InChI Key

BUOJSRKCUHUERC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137989

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.795

Distribution Coefficient, logD

2.794

Water Solubility, LogSw

-3.25

Polar Surface Area

64.588

Acid Dissociation Constant (pKa)

28.13

Base Dissociation Constant (pKb)

4.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G373-3305 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Proteases
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G373-3305 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3305?
Check Price and Availability of G373-3305, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-3305 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3305
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3305
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3305 available by request