G373-3319 Screening compound: 4-[(4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazin-1-yl)sulfonyl]-2,1,3-benzothiadiazole

G373-3319 Screening compound: 4-[(4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazin-1-yl)sulfonyl]-2,1,3-benzothiadiazole
G373-3319 Screening compound: 4-[(4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazin-1-yl)sulfonyl]-2,1,3-benzothiadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3319
4-[(4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazin-1-yl)sulfonyl]-2,1,3-benzothiadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3319

Molecular Formula

C24H23N7O2S2 (C24 H23 N7 O2 S2)

Compound Name

4-[(4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazin-1-yl)sulfonyl]-2,1,3-benzothiadiazole

IUPAC name

4-[(4-{[3-(4-methylphenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}piperazin-1-yl)sulfonyl]-213-benzothiadiazole

SMILES

Cc(cc1)ccc1-n1c(nccc2)c2nc1CN(CC1)CCN1S(c1cccc2nsnc12)(=O)=O

InChI

InChI=1S/C24H23N7O2S2/c1-17-7-9-18(10-8-17)31-22(26-20-5-3-11-25-24(20)31)16-29-12-14-30(15-13-29)35(32,33)21-6-2-4-19-23(21)28-34-27-19/h2-11H,12-16H2,1H3

InChI Key

OBPHPKIIRKMDRY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137996

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

505.62

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.280

Distribution Coefficient, logD

3.278

Water Solubility, LogSw

-3.35

Polar Surface Area

77.997

Acid Dissociation Constant (pKa)

28.13

Base Dissociation Constant (pKb)

4.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G373-3319 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with G373-3319 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3319?
Check Price and Availability of G373-3319, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-3319 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3319
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3319
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3319 available by request