G373-3320 Screening compound: 1-(2,5-dimethoxybenzenesulfonyl)-4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine

G373-3320 Screening compound: 1-(2,5-dimethoxybenzenesulfonyl)-4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine
G373-3320 Screening compound: 1-(2,5-dimethoxybenzenesulfonyl)-4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3320
1-(2,5-dimethoxybenzenesulfonyl)-4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3320

Molecular Formula

C26H29N5O4S (C26 H29 N5 O4 S)

Compound Name

1-(2,5-dimethoxybenzenesulfonyl)-4-{[3-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine

IUPAC name

1-(25-dimethoxybenzenesulfonyl)-4-{[3-(4-methylphenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}piperazine

SMILES

Cc(cc1)ccc1-n1c(nccc2)c2nc1CN(CC1)CCN1S(c(cc(cc1)OC)c1OC)(=O)=O

InChI

InChI=1S/C26H29N5O4S/c1-19-6-8-20(9-7-19)31-25(28-22-5-4-12-27-26(22)31)18-29-13-15-30(16-14-29)36(32,33)24-17-21(34-2)10-11-23(24)35-3/h4-12,17H,13-16,18H2,1-3H3

InChI Key

KSWMZIXTJBDTAS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137997

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

507.61

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.181

Distribution Coefficient, logD

3.180

Water Solubility, LogSw

-3.27

Polar Surface Area

72.219

Acid Dissociation Constant (pKa)

28.13

Base Dissociation Constant (pKb)

4.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.80

G373-3320 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G373-3320 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3320?
Check Price and Availability of G373-3320, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-3320 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3320
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3320
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3320 available by request