G373-3531 Screening compound: N-(3,4-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

G373-3531 Screening compound: N-(3,4-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide
G373-3531 Screening compound: N-(3,4-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3531
N-(3,4-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3531

Molecular Formula

C28H32N6O3 (C28 H32 N6 O3)

Compound Name

N-(3,4-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

IUPAC name

N-(34-dimethoxyphenyl)-4-{[3-(35-dimethylphenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

SMILES

Cc1cc(-n2c(nccc3)c3nc2CN(CC2)CCN2C(Nc(cc2)cc(OC)c2OC)=O)cc(C)c1

InChI

InChI=1S/C28H32N6O3/c1-19-14-20(2)16-22(15-19)34-26(31-23-6-5-9-29-27(23)34)18-32-10-12-33(13-11-32)28(35)30-21-7-8-24(36-3)25(17-21)37-4/h5-9,14-17H,10-13,18H2,1-4H3,(H,30,35)

InChI Key

SMBHOEPPSBEPOB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27138049

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

500.6

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.524

Distribution Coefficient, logD

3.417

Water Solubility, LogSw

-3.55

Polar Surface Area

66.064

Acid Dissociation Constant (pKa)

12.72

Base Dissociation Constant (pKb)

6.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

G373-3531 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

PI3K-Targeted Library (17255 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with G373-3531 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3531?
Check Price and Availability of G373-3531, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-3531 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3531
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3531
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3531 available by request