G373-3533 Screening compound: N-(2,5-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

G373-3533 Screening compound: N-(2,5-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide
G373-3533 Screening compound: N-(2,5-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3533
N-(2,5-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3533

Molecular Formula

C28H32N6O3 (C28 H32 N6 O3)

Compound Name

N-(2,5-dimethoxyphenyl)-4-{[3-(3,5-dimethylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

IUPAC name

N-(25-dimethoxyphenyl)-4-{[3-(35-dimethylphenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}piperazine-1-carboxamide

SMILES

Cc1cc(-n2c(nccc3)c3nc2CN(CC2)CCN2C(Nc(cc(cc2)OC)c2OC)=O)cc(C)c1

InChI

InChI=1S/C28H32N6O3/c1-19-14-20(2)16-21(15-19)34-26(30-23-6-5-9-29-27(23)34)18-32-10-12-33(13-11-32)28(35)31-24-17-22(36-3)7-8-25(24)37-4/h5-9,14-17H,10-13,18H2,1-4H3,(H,31,35)

InChI Key

VGHYCSZGPORQPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27138050

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

500.6

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.068

Distribution Coefficient, logD

3.962

Water Solubility, LogSw

-4.14

Polar Surface Area

65.279

Acid Dissociation Constant (pKa)

11.60

Base Dissociation Constant (pKb)

6.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

G373-3533 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with G373-3533 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3533?
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What is the minimum amount of G373-3533 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3533
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3533
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3533 available by request