G373-3778 Screening compound: 4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(3-methylbutyl)piperazine-1-carboxamide

G373-3778 Screening compound: 4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(3-methylbutyl)piperazine-1-carboxamide
G373-3778 Screening compound: 4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(3-methylbutyl)piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3778
4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(3-methylbutyl)piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3778

Molecular Formula

C23H29FN6O (C23 H29 FN6 O)

Compound Name

4-{[3-(3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(3-methylbutyl)piperazine-1-carboxamide

IUPAC name

4-{[3-(3-fluorophenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}-N-(3-methylbutyl)piperazine-1-carboxamide

SMILES

CC(C)CCNC(N1CCN(Cc2nc3cccnc3n2-c2cccc(F)c2)CC1)=O

InChI

InChI=1S/C23H29FN6O/c1-17(2)8-10-26-23(31)29-13-11-28(12-14-29)16-21-27-20-7-4-9-25-22(20)30(21)19-6-3-5-18(24)15-19/h3-7,9,15,17H,8,10-14,16H2,1-2H3,(H,26,31)

InChI Key

NFDFEFVUKSBZPK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27138124

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.208

Distribution Coefficient, logD

3.206

Water Solubility, LogSw

-3.38

Polar Surface Area

52.238

Acid Dissociation Constant (pKa)

15.70

Base Dissociation Constant (pKb)

4.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

G373-3778 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

GPCR Targeted Library (31838 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
Targets:
  • Proteases
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with G373-3778 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3778?
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What is the minimum amount of G373-3778 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3778
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3778
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3778 available by request