G373-3837 Screening compound: 1-(2,6-dimethylphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea

G373-3837 Screening compound: 1-(2,6-dimethylphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea
G373-3837 Screening compound: 1-(2,6-dimethylphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3837
1-(2,6-dimethylphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3837

Molecular Formula

C19H20F3N5O (C19 H20 F3 N5 O)

Compound Name

1-(2,6-dimethylphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea

IUPAC name

1-(26-dimethylphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[45-b]pyridin-3-yl]propyl}urea

SMILES

Cc1cccc(C)c1NC(NCCCn1c(nccc2)c2nc1C(F)(F)F)=O

InChI

InChI=1S/C19H20F3N5O/c1-12-6-3-7-13(2)15(12)26-18(28)24-10-5-11-27-16-14(8-4-9-23-16)25-17(27)19(20,21)22/h3-4,6-9H,5,10-11H2,1-2H3,(H2,24,26,28)

InChI Key

IELLYDGKKQCGCZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28119771

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.246

Distribution Coefficient, logD

3.246

Water Solubility, LogSw

-3.11

Polar Surface Area

52.395

Acid Dissociation Constant (pKa)

13.34

Base Dissociation Constant (pKb)

1.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

G373-3837 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G373-3837 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3837?
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What is the minimum amount of G373-3837 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3837
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3837
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3837 available by request