G373-3838 Screening compound: 1-(3-chloro-4-methoxyphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea

G373-3838 Screening compound: 1-(3-chloro-4-methoxyphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea
G373-3838 Screening compound: 1-(3-chloro-4-methoxyphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3838
1-(3-chloro-4-methoxyphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3838

Molecular Formula

C18H17ClF3N5O2 (C18 H17 ClF3 N5 O2)

Compound Name

1-(3-chloro-4-methoxyphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]propyl}urea

IUPAC name

1-(3-chloro-4-methoxyphenyl)-3-{3-[2-(trifluoromethyl)-3H-imidazo[45-b]pyridin-3-yl]propyl}urea

SMILES

COc(ccc(NC(NCCCn1c2ncccc2nc1C(F)(F)F)=O)c1)c1Cl

InChI

InChI=1S/C18H17ClF3N5O2/c1-29-14-6-5-11(10-12(14)19)25-17(28)24-8-3-9-27-15-13(4-2-7-23-15)26-16(27)18(20,21)22/h2,4-7,10H,3,8-9H2,1H3,(H2,24,25,28)

InChI Key

SQQMCEFEJYATDP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28119772

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.81

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.604

Distribution Coefficient, logD

3.604

Water Solubility, LogSw

-3.81

Polar Surface Area

61.421

Acid Dissociation Constant (pKa)

11.61

Base Dissociation Constant (pKb)

1.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G373-3838 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G373-3838 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3838?
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What is the minimum amount of G373-3838 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3838
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3838
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3838 available by request