G373-3901 Screening compound: 5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-3-(pyrrolidine-1-carbonyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one

G373-3901 Screening compound: 5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-3-(pyrrolidine-1-carbonyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one
G373-3901 Screening compound: 5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-3-(pyrrolidine-1-carbonyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3901
5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-3-(pyrrolidine-1-carbonyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3901

Molecular Formula

C28H34N6O3 (C28 H34 N6 O3)

Compound Name

5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-3-(pyrrolidine-1-carbonyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one

IUPAC name

5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-3-(pyrrolidine-1-carbonyl)-5H6H6aH7H8H9H10H-pyrido[12-a]quinoxalin-6-one

SMILES

O=C(CN1c(cc(cc2)C(N3CCCC3)=O)c2N(CCCC2)C2C1=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C28H34N6O3/c35-26(31-17-15-30(16-18-31)25-8-1-3-11-29-25)20-34-24-19-21(27(36)32-12-5-6-13-32)9-10-22(24)33-14-4-2-7-23(33)28(34)37/h1,3,8-11,19,23H,2,4-7,12-18,20H2/t23-/m0/s1

InChI Key

QKOVGCYJRDFPGI-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD27138155

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

502.62

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.833

Distribution Coefficient, logD

1.824

Water Solubility, LogSw

-2.25

Polar Surface Area

62.970

Acid Dissociation Constant (pKa)

15.09

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

G373-3901 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G373-3901 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3901?
Check Price and Availability of G373-3901, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-3901 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3901
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3901
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3901 available by request