G373-4054 Screening compound: N-(2,4-difluorophenyl)-4-[(5-phenyl-1,3-benzoxazol-2-yl)methyl]piperazine-1-carboxamide

G373-4054 Screening compound: N-(2,4-difluorophenyl)-4-[(5-phenyl-1,3-benzoxazol-2-yl)methyl]piperazine-1-carboxamide
G373-4054 Screening compound: N-(2,4-difluorophenyl)-4-[(5-phenyl-1,3-benzoxazol-2-yl)methyl]piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-4054
N-(2,4-difluorophenyl)-4-[(5-phenyl-1,3-benzoxazol-2-yl)methyl]piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-4054

Molecular Formula

C25H22F2N4O2 (C25 H22 F2 N4 O2)

Compound Name

N-(2,4-difluorophenyl)-4-[(5-phenyl-1,3-benzoxazol-2-yl)methyl]piperazine-1-carboxamide

IUPAC name

N-(24-difluorophenyl)-4-[(5-phenyl-13-benzoxazol-2-yl)methyl]piperazine-1-carboxamide

SMILES

O=C(Nc(ccc(F)c1)c1F)N1CCN(Cc2nc(cc(cc3)-c4ccccc4)c3o2)CC1

InChI

InChI=1S/C25H22F2N4O2/c26-19-7-8-21(20(27)15-19)29-25(32)31-12-10-30(11-13-31)16-24-28-22-14-18(6-9-23(22)33-24)17-4-2-1-3-5-17/h1-9,14-15H,10-13,16H2,(H,29,32)

InChI Key

XZDWWCHLQOOJRH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27138197

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.840

Distribution Coefficient, logD

4.831

Water Solubility, LogSw

-4.93

Polar Surface Area

45.026

Acid Dissociation Constant (pKa)

10.34

Base Dissociation Constant (pKb)

5.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G373-4054 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G373-4054 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-4054?
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What is the minimum amount of G373-4054 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-4054
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-4054
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-4054 available by request