G374-0693 Screening compound: 5-[2-(4-benzylpiperidin-1-yl)-2-oxoethyl]-2-(4-chlorophenyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-4-one

G374-0693 Screening compound: 5-[2-(4-benzylpiperidin-1-yl)-2-oxoethyl]-2-(4-chlorophenyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-4-one
G374-0693 Screening compound: 5-[2-(4-benzylpiperidin-1-yl)-2-oxoethyl]-2-(4-chlorophenyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G374-0693
5-[2-(4-benzylpiperidin-1-yl)-2-oxoethyl]-2-(4-chlorophenyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G374-0693

Molecular Formula

C26H27ClN4O2 (C26 H27 ClN4 O2)

Compound Name

5-[2-(4-benzylpiperidin-1-yl)-2-oxoethyl]-2-(4-chlorophenyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-4-one

IUPAC name

5-[2-(4-benzylpiperidin-1-yl)-2-oxoethyl]-2-(4-chlorophenyl)-4H5H6H7H-pyrazolo[15-a]pyrazin-4-one

SMILES

O=C(CN(CCn(c1c2)nc2-c(cc2)ccc2Cl)C1=O)N1CCC(Cc2ccccc2)CC1

InChI

InChI=1S/C26H27ClN4O2/c27-22-8-6-21(7-9-22)23-17-24-26(33)30(14-15-31(24)28-23)18-25(32)29-12-10-20(11-13-29)16-19-4-2-1-3-5-19/h1-9,17,20H,10-16,18H2

InChI Key

XDVSUNYWDYMCJF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15006461

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.98

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.495

Distribution Coefficient, logD

4.495

Water Solubility, LogSw

-4.87

Polar Surface Area

45.900

Acid Dissociation Constant (pKa)

22.21

Base Dissociation Constant (pKb)

1.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

G374-0693 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G374-0693 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G374-0693?
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What is the minimum amount of G374-0693 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G374-0693
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G374-0693
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G374-0693 available by request