G374-0860 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl]-N-cyclohexylacetamide

G374-0860 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl]-N-cyclohexylacetamide
G374-0860 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl]-N-cyclohexylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G374-0860
2-[2-(4-chlorophenyl)-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl]-N-cyclohexylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G374-0860

Molecular Formula

C20H23ClN4O2 (C20 H23 ClN4 O2)

Compound Name

2-[2-(4-chlorophenyl)-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl]-N-cyclohexylacetamide

IUPAC name

2-[2-(4-chlorophenyl)-4-oxo-4H5H6H7H-pyrazolo[15-a]pyrazin-5-yl]-N-cyclohexylacetamide

SMILES

O=C(CN(CCn(c1c2)nc2-c(cc2)ccc2Cl)C1=O)NC1CCCCC1

InChI

InChI=1S/C20H23ClN4O2/c21-15-8-6-14(7-9-15)17-12-18-20(27)24(10-11-25(18)23-17)13-19(26)22-16-4-2-1-3-5-16/h6-9,12,16H,1-5,10-11,13H2,(H,22,26)

InChI Key

WEFKCEYMTIOOMO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15006485

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.88

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.374

Distribution Coefficient, logD

3.374

Water Solubility, LogSw

-3.95

Polar Surface Area

53.976

Acid Dissociation Constant (pKa)

15.71

Base Dissociation Constant (pKb)

3.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

G374-0860 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G374-0860 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G374-0860?
Check Price and Availability of G374-0860, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G374-0860 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G374-0860
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G374-0860
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G374-0860 available by request