G374-0936 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-5-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide

G374-0936 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-5-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide
G374-0936 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-5-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G374-0936
2-[2-(4-chlorophenyl)-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-5-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G374-0936

Molecular Formula

C20H19ClN4O2S (C20 H19 ClN4 O2 S)

Compound Name

2-[2-(4-chlorophenyl)-4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-5-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide

IUPAC name

2-[2-(4-chlorophenyl)-4-oxo-4H5H6H7H-pyrazolo[15-a]pyrazin-5-yl]-N-[2-(thiophen-2-yl)ethyl]acetamide

SMILES

O=C(CN(CCn(c1c2)nc2-c(cc2)ccc2Cl)C1=O)NCCc1cccs1

InChI

InChI=1S/C20H19ClN4O2S/c21-15-5-3-14(4-6-15)17-12-18-20(27)24(9-10-25(18)23-17)13-19(26)22-8-7-16-2-1-11-28-16/h1-6,11-12H,7-10,13H2,(H,22,26)

InChI Key

HPTMHRUDHYUUQG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15006501

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.92

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.887

Distribution Coefficient, logD

2.887

Water Solubility, LogSw

-3.66

Polar Surface Area

55.110

Acid Dissociation Constant (pKa)

14.75

Base Dissociation Constant (pKb)

2.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G374-0936 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G374-0936 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G374-0936?
Check Price and Availability of G374-0936, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G374-0936 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G374-0936
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G374-0936
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G374-0936 available by request