G375-1102 Screening compound: N-(2,5-difluorophenyl)-2-[5-(4-fluorophenyl)-6,7-dimethyl-2-oxo-1H,2H,3H-thieno[2,3-e][1,4]diazepin-1-yl]acetamide

G375-1102 Screening compound: N-(2,5-difluorophenyl)-2-[5-(4-fluorophenyl)-6,7-dimethyl-2-oxo-1H,2H,3H-thieno[2,3-e][1,4]diazepin-1-yl]acetamide
G375-1102 Screening compound: N-(2,5-difluorophenyl)-2-[5-(4-fluorophenyl)-6,7-dimethyl-2-oxo-1H,2H,3H-thieno[2,3-e][1,4]diazepin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G375-1102
N-(2,5-difluorophenyl)-2-[5-(4-fluorophenyl)-6,7-dimethyl-2-oxo-1H,2H,3H-thieno[2,3-e][1,4]diazepin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G375-1102

Molecular Formula

C23H18F3N3O2S (C23 H18 F3 N3 O2 S)

Compound Name

N-(2,5-difluorophenyl)-2-[5-(4-fluorophenyl)-6,7-dimethyl-2-oxo-1H,2H,3H-thieno[2,3-e][1,4]diazepin-1-yl]acetamide

IUPAC name

N-(25-difluorophenyl)-2-[5-(4-fluorophenyl)-67-dimethyl-2-oxo-1H2H3H-thieno[23-e][14]diazepin-1-yl]acetamide

SMILES

Cc1c(C)sc(N2CC(Nc(cc(cc3)F)c3F)=O)c1C(c(cc1)ccc1F)=NCC2=O

InChI

InChI=1S/C23H18F3N3O2S/c1-12-13(2)32-23-21(12)22(14-3-5-15(24)6-4-14)27-10-20(31)29(23)11-19(30)28-18-9-16(25)7-8-17(18)26/h3-9H,10-11H2,1-2H3,(H,28,30)

InChI Key

BVEKTUYVCISTTD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15006539

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.441

Distribution Coefficient, logD

4.428

Water Solubility, LogSw

-4.40

Polar Surface Area

46.845

Acid Dissociation Constant (pKa)

8.92

Base Dissociation Constant (pKb)

1.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

G375-1102 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antiviral Library (67538 compounds)

Bromodomain Modulators Library (5801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G375-1102 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G375-1102?
Check Price and Availability of G375-1102, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G375-1102 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G375-1102
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G375-1102
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G375-1102 available by request