G375-2849 Screening compound: 5-(4-methoxyphenyl)-1-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-1,3,6,7,8,9-hexahydro-2H-[1]benzothieno[2,3-e][1,4]diazepin-2-one

G375-2849 Screening compound: 5-(4-methoxyphenyl)-1-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-1,3,6,7,8,9-hexahydro-2H-[1]benzothieno[2,3-e][1,4]diazepin-2-one
G375-2849 Screening compound: 5-(4-methoxyphenyl)-1-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-1,3,6,7,8,9-hexahydro-2H-[1]benzothieno[2,3-e][1,4]diazepin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G375-2849
5-(4-methoxyphenyl)-1-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-1,3,6,7,8,9-hexahydro-2H-[1]benzothieno[2,3-e][1,4]diazepin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G375-2849

Molecular Formula

C29H27N3O3S (C29 H27 N3 O3 S)

Compound Name

5-(4-methoxyphenyl)-1-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-1,3,6,7,8,9-hexahydro-2H-[1]benzothieno[2,3-e][1,4]diazepin-2-one

IUPAC name

14-(4-methoxyphenyl)-10-[(5-methyl-2-phenyl-13-oxazol-4-yl)methyl]-8-thia-1013-diazatricyclo[7.5.0.0^{27}]tetradeca-1(9)2(7)13-trien-11-one

SMILES

Cc1c(CN(c(sc2c3CCCC2)c3C(c(cc2)ccc2OC)=NC2)C2=O)nc(-c2ccccc2)o1

InChI

InChI=1S/C29H27N3O3S/c1-18-23(31-28(35-18)20-8-4-3-5-9-20)17-32-25(33)16-30-27(19-12-14-21(34-2)15-13-19)26-22-10-6-7-11-24(22)36-29(26)32/h3-5,8-9,12-15H,6-7,10-11,16-17H2,1-2H3

InChI Key

MANWWLBWZFVENB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15006576

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.62

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.580

Distribution Coefficient, logD

5.580

Water Solubility, LogSw

-5.52

Polar Surface Area

49.980

Acid Dissociation Constant (pKa)

25.46

Base Dissociation Constant (pKb)

0.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.60

G375-2849 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antiviral Library (67538 compounds)

Bromodomain Modulators Library (5801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G375-2849 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G375-2849?
Check Price and Availability of G375-2849, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G375-2849 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G375-2849
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G375-2849
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G375-2849 available by request