G389-1244 Screening compound: methyl 7-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-6-{[3-(propan-2-yloxy)propyl]carbamoyl}-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-carboxylate

G389-1244 Screening compound: methyl 7-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-6-{[3-(propan-2-yloxy)propyl]carbamoyl}-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-carboxylate
G389-1244 Screening compound: methyl 7-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-6-{[3-(propan-2-yloxy)propyl]carbamoyl}-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G389-1244
methyl 7-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-6-{[3-(propan-2-yloxy)propyl]carbamoyl}-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G389-1244

Molecular Formula

C24H32N4O6 (C24 H32 N4 O6)

Compound Name

methyl 7-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-6-{[3-(propan-2-yloxy)propyl]carbamoyl}-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-carboxylate

IUPAC name

methyl 7-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-6-{[3-(propan-2-yloxy)propyl]carbamoyl}-5H6H7H8H-imidazo[15-a]pyrazine-1-carboxylate

SMILES

CC(C)OCCCNC(C(C)(Cn1c2c(C(OC)=O)nc1)N(Cc(cc1)ccc1OC)C2=O)=O

InChI

InChI=1S/C24H32N4O6/c1-16(2)34-12-6-11-25-23(31)24(3)14-27-15-26-19(22(30)33-5)20(27)21(29)28(24)13-17-7-9-18(32-4)10-8-17/h7-10,15-16H,6,11-14H2,1-5H3,(H,25,31)/t24-/m0/s1

InChI Key

JHCHDHVPTFCGJU-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD27138530

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.54

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.513

Distribution Coefficient, logD

1.513

Water Solubility, LogSw

-2.15

Polar Surface Area

87.717

Acid Dissociation Constant (pKa)

14.84

Base Dissociation Constant (pKb)

3.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

G389-1244 in Drug Discovery

Included in Screening Libraries

Cyclic Ugi PPI Library (9586 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Developmental Pathway (Hh/Wnt) Set (2238 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others

References: we are preparing a list of scientific research reports with G389-1244 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G389-1244?
Check Price and Availability of G389-1244, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G389-1244 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G389-1244
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G389-1244
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G389-1244 available by request