G394-0278 Screening compound: N-(2-{cyclopentyl[(furan-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

G394-0278 Screening compound: N-(2-{cyclopentyl[(furan-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide
G394-0278 Screening compound: N-(2-{cyclopentyl[(furan-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G394-0278
N-(2-{cyclopentyl[(furan-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G394-0278

Molecular Formula

C25H34N6O2S (C25 H34 N6 O2 S)

Compound Name

N-(2-{cyclopentyl[(furan-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

IUPAC name

N-(2-{cyclopentyl[(furan-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[23-d]pyrimidine-6-carboxamide

SMILES

Cc1c(C(NCCN(Cc2ccco2)C2CCCC2)=O)sc2ncnc(N3CCN(C)CC3)c12

InChI

InChI=1S/C25H34N6O2S/c1-18-21-23(30-13-11-29(2)12-14-30)27-17-28-25(21)34-22(18)24(32)26-9-10-31(19-6-3-4-7-19)16-20-8-5-15-33-20/h5,8,15,17,19H,3-4,6-7,9-14,16H2,1-2H3,(H,26,32)

InChI Key

MECMJDWGZTWJFN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15007310

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.65

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.481

Distribution Coefficient, logD

3.017

Water Solubility, LogSw

-3.93

Polar Surface Area

63.211

Acid Dissociation Constant (pKa)

11.95

Base Dissociation Constant (pKb)

7.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.00

G394-0278 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G394-0278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G394-0278?
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What is the minimum amount of G394-0278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G394-0278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G394-0278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G394-0278 available by request