G394-0327 Screening compound: N-(2-{butyl[(thiophen-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

G394-0327 Screening compound: N-(2-{butyl[(thiophen-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide
G394-0327 Screening compound: N-(2-{butyl[(thiophen-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G394-0327
N-(2-{butyl[(thiophen-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G394-0327

Molecular Formula

C24H34N6OS2 (C24 H34 N6 OS2)

Compound Name

N-(2-{butyl[(thiophen-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

IUPAC name

N-(2-{butyl[(thiophen-2-yl)methyl]amino}ethyl)-5-methyl-4-(4-methylpiperazin-1-yl)thieno[23-d]pyrimidine-6-carboxamide

SMILES

CCCCN(CCNC(c1c(C)c2c(N3CCN(C)CC3)ncnc2s1)=O)Cc1cccs1

InChI

InChI=1S/C24H34N6OS2/c1-4-5-9-29(16-19-7-6-15-32-19)10-8-25-23(31)21-18(2)20-22(26-17-27-24(20)33-21)30-13-11-28(3)12-14-30/h6-7,15,17H,4-5,8-14,16H2,1-3H3,(H,25,31)

InChI Key

PFQDKASACRZVAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15007330

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.71

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.207

Distribution Coefficient, logD

3.742

Water Solubility, LogSw

-4.04

Polar Surface Area

57.228

Acid Dissociation Constant (pKa)

11.95

Base Dissociation Constant (pKb)

7.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.20

G394-0327 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G394-0327 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G394-0327?
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What is the minimum amount of G394-0327 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G394-0327
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G394-0327
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G394-0327 available by request