G394-0809 Screening compound: 5-methyl-N-[4-(propan-2-yl)phenyl]-4-(4-propylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

G394-0809 Screening compound: 5-methyl-N-[4-(propan-2-yl)phenyl]-4-(4-propylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide
G394-0809 Screening compound: 5-methyl-N-[4-(propan-2-yl)phenyl]-4-(4-propylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G394-0809
5-methyl-N-[4-(propan-2-yl)phenyl]-4-(4-propylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G394-0809

Molecular Formula

C24H31N5OS (C24 H31 N5 OS)

Compound Name

5-methyl-N-[4-(propan-2-yl)phenyl]-4-(4-propylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide

IUPAC name

5-methyl-N-[4-(propan-2-yl)phenyl]-4-(4-propylpiperazin-1-yl)thieno[23-d]pyrimidine-6-carboxamide

SMILES

CCCN(CC1)CCN1c1c(c(C)c(C(Nc2ccc(C(C)C)cc2)=O)s2)c2ncn1

InChI

InChI=1S/C24H31N5OS/c1-5-10-28-11-13-29(14-12-28)22-20-17(4)21(31-24(20)26-15-25-22)23(30)27-19-8-6-18(7-9-19)16(2)3/h6-9,15-16H,5,10-14H2,1-4H3,(H,27,30)

InChI Key

KPBZYKPRLUTXQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15007431

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.61

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.541

Distribution Coefficient, logD

4.956

Water Solubility, LogSw

-5.69

Polar Surface Area

51.420

Acid Dissociation Constant (pKa)

10.55

Base Dissociation Constant (pKb)

7.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

G394-0809 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Human Kinases Annotated Library (2415 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G394-0809 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G394-0809?
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What is the minimum amount of G394-0809 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G394-0809
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G394-0809
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G394-0809 available by request