G395-0011 Screening compound: 3-[6-(diethylamino)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}propan-1-one

G395-0011 Screening compound: 3-[6-(diethylamino)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}propan-1-one
G395-0011 Screening compound: 3-[6-(diethylamino)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G395-0011
3-[6-(diethylamino)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G395-0011

Molecular Formula

C19H28N6O3 (C19 H28 N6 O3)

Compound Name

3-[6-(diethylamino)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}propan-1-one

IUPAC name

3-[6-(diethylamino)-[124]triazolo[43-b]pyridazin-3-yl]-1-{14-dioxa-8-azaspiro[4.5]decan-8-yl}propan-1-one

SMILES

CCN(CC)c(cc1)nn2c1nnc2CCC(N(CC1)CCC11OCCO1)=O

InChI

InChI=1S/C19H28N6O3/c1-3-23(4-2)17-6-5-15-20-21-16(25(15)22-17)7-8-18(26)24-11-9-19(10-12-24)27-13-14-28-19/h5-6H,3-4,7-14H2,1-2H3

InChI Key

JYDIJRRHIYQFNS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15007527

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.522

Distribution Coefficient, logD

0.522

Water Solubility, LogSw

-1.43

Polar Surface Area

66.402

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

2.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

68.40

G395-0011 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G395-0011 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G395-0011?
Check Price and Availability of G395-0011, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G395-0011 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G395-0011
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G395-0011
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G395-0011 available by request