G395-1009 Screening compound: 1-[4-(2-fluorophenyl)piperazin-1-yl]-3-(6-{[(pyridin-3-yl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propan-1-one

G395-1009 Screening compound: 1-[4-(2-fluorophenyl)piperazin-1-yl]-3-(6-{[(pyridin-3-yl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propan-1-one
G395-1009 Screening compound: 1-[4-(2-fluorophenyl)piperazin-1-yl]-3-(6-{[(pyridin-3-yl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G395-1009
1-[4-(2-fluorophenyl)piperazin-1-yl]-3-(6-{[(pyridin-3-yl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G395-1009

Molecular Formula

C24H25FN8O (C24 H25 FN8 O)

Compound Name

1-[4-(2-fluorophenyl)piperazin-1-yl]-3-(6-{[(pyridin-3-yl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propan-1-one

IUPAC name

1-[4-(2-fluorophenyl)piperazin-1-yl]-3-(6-{[(pyridin-3-yl)methyl]amino}-[124]triazolo[43-b]pyridazin-3-yl)propan-1-one

SMILES

O=C(CCc1nnc(cc2)n1nc2NCc1cnccc1)N(CC1)CCN1c(cccc1)c1F

InChI

InChI=1S/C24H25FN8O/c25-19-5-1-2-6-20(19)31-12-14-32(15-13-31)24(34)10-9-23-29-28-22-8-7-21(30-33(22)23)27-17-18-4-3-11-26-16-18/h1-8,11,16H,9-10,12-15,17H2,(H,27,30)

InChI Key

PVDXMELIDPDQHP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15007843

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.314

Distribution Coefficient, logD

1.285

Water Solubility, LogSw

-1.12

Polar Surface Area

73.045

Acid Dissociation Constant (pKa)

17.55

Base Dissociation Constant (pKb)

6.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

G395-1009 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G395-1009 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G395-1009?
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What is the minimum amount of G395-1009 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G395-1009
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G395-1009
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G395-1009 available by request