G395-1306 Screening compound: N-(3-acetylphenyl)-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

G395-1306 Screening compound: N-(3-acetylphenyl)-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide
G395-1306 Screening compound: N-(3-acetylphenyl)-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G395-1306
N-(3-acetylphenyl)-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G395-1306

Molecular Formula

C23H21FN6O2 (C23 H21 FN6 O2)

Compound Name

N-(3-acetylphenyl)-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

IUPAC name

N-(3-acetylphenyl)-3-(6-{[(4-fluorophenyl)methyl]amino}-[124]triazolo[43-b]pyridazin-3-yl)propanamide

SMILES

CC(c1cccc(NC(CCc2nnc(cc3)n2nc3NCc(cc2)ccc2F)=O)c1)=O

InChI

InChI=1S/C23H21FN6O2/c1-15(31)17-3-2-4-19(13-17)26-23(32)12-11-22-28-27-21-10-9-20(29-30(21)22)25-14-16-5-7-18(24)8-6-16/h2-10,13H,11-12,14H2,1H3,(H,25,29)(H,26,32)

InChI Key

UHXJYRVIFYSWDD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15007991

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.205

Distribution Coefficient, logD

2.205

Water Solubility, LogSw

-2.87

Polar Surface Area

81.151

Acid Dissociation Constant (pKa)

10.80

Base Dissociation Constant (pKb)

1.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

G395-1306 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G395-1306 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G395-1306?
Check Price and Availability of G395-1306, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G395-1306 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G395-1306
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G395-1306
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G395-1306 available by request