G395-1341 Screening compound: N-[(1-cyclopentylpyrrolidin-3-yl)methyl]-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

G395-1341 Screening compound: N-[(1-cyclopentylpyrrolidin-3-yl)methyl]-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide
G395-1341 Screening compound: N-[(1-cyclopentylpyrrolidin-3-yl)methyl]-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G395-1341
N-[(1-cyclopentylpyrrolidin-3-yl)methyl]-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G395-1341

Molecular Formula

C25H32FN7O (C25 H32 FN7 O)

Compound Name

N-[(1-cyclopentylpyrrolidin-3-yl)methyl]-3-(6-{[(4-fluorophenyl)methyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

IUPAC name

N-[(1-cyclopentylpyrrolidin-3-yl)methyl]-3-(6-{[(4-fluorophenyl)methyl]amino}-[124]triazolo[43-b]pyridazin-3-yl)propanamide

SMILES

O=C(CCc1nnc(cc2)n1nc2NCc(cc1)ccc1F)NCC(CC1)CN1C1CCCC1

InChI

InChI=1S/C25H32FN7O/c26-20-7-5-18(6-8-20)15-27-22-9-10-23-29-30-24(33(23)31-22)11-12-25(34)28-16-19-13-14-32(17-19)21-3-1-2-4-21/h5-10,19,21H,1-4,11-17H2,(H,27,31)(H,28,34)/t19-/m1/s1

InChI Key

PIHHDRAZXXVYPJ-LJQANCHMSA-N

MDL Number (MFCD)

MFCD15008020

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.918

Distribution Coefficient, logD

-2.682

Water Solubility, LogSw

-2.28

Polar Surface Area

72.597

Acid Dissociation Constant (pKa)

15.25

Base Dissociation Constant (pKb)

12.00

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.00

G395-1341 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G395-1341 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G395-1341?
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What is the minimum amount of G395-1341 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G395-1341
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G395-1341
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G395-1341 available by request