G395-1711 Screening compound: N-(2,5-diethoxyphenyl)-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

G395-1711 Screening compound: N-(2,5-diethoxyphenyl)-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide
G395-1711 Screening compound: N-(2,5-diethoxyphenyl)-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G395-1711
N-(2,5-diethoxyphenyl)-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G395-1711

Molecular Formula

C25H33N7O4 (C25 H33 N7 O4)

Compound Name

N-(2,5-diethoxyphenyl)-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

IUPAC name

N-(25-diethoxyphenyl)-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[124]triazolo[43-b]pyridazin-3-yl)propanamide

SMILES

CCOc(cc1)cc(NC(CCc2nnc(cc3)n2nc3NCCCN(CCC2)C2=O)=O)c1OCC

InChI

InChI=1S/C25H33N7O4/c1-3-35-18-8-9-20(36-4-2)19(17-18)27-24(33)13-12-23-29-28-22-11-10-21(30-32(22)23)26-14-6-16-31-15-5-7-25(31)34/h8-11,17H,3-7,12-16H2,1-2H3,(H,26,30)(H,27,33)

InChI Key

VJIGHDWMDPOVQY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15008211

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

14.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

1.061

Distribution Coefficient, logD

1.060

Water Solubility, LogSw

-2.20

Polar Surface Area

98.314

Acid Dissociation Constant (pKa)

10.11

Base Dissociation Constant (pKb)

1.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.00

G395-1711 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with G395-1711 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G395-1711?
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What is the minimum amount of G395-1711 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G395-1711
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G395-1711
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G395-1711 available by request