G397-0171 Screening compound: N~2~-[2-(dipropylamino)ethyl]-1-[5-(2-oxo-1-pyrrolidinyl)-1,3,4-thiadiazol-2-yl]-2-pyrrolidinecarboxamide

G397-0171 Screening compound: N~2~-[2-(dipropylamino)ethyl]-1-[5-(2-oxo-1-pyrrolidinyl)-1,3,4-thiadiazol-2-yl]-2-pyrrolidinecarboxamide
G397-0171 Screening compound: N~2~-[2-(dipropylamino)ethyl]-1-[5-(2-oxo-1-pyrrolidinyl)-1,3,4-thiadiazol-2-yl]-2-pyrrolidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G397-0171
N~2~-[2-(dipropylamino)ethyl]-1-[5-(2-oxo-1-pyrrolidinyl)-1,3,4-thiadiazol-2-yl]-2-pyrrolidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G397-0171

Molecular Formula

C19H32N6O2S (C19 H32 N6 O2 S)

Compound Name

N~2~-[2-(dipropylamino)ethyl]-1-[5-(2-oxo-1-pyrrolidinyl)-1,3,4-thiadiazol-2-yl]-2-pyrrolidinecarboxamide

IUPAC name

N-[2-(dipropylamino)ethyl]-1-[5-(2-oxopyrrolidin-1-yl)-134-thiadiazol-2-yl]pyrrolidine-2-carboxamide

SMILES

CCCN(CCC)CCNC(C(CCC1)N1c1nnc(N(CCC2)C2=O)s1)=O

InChI

InChI=1S/C19H32N6O2S/c1-3-10-23(11-4-2)14-9-20-17(27)15-7-5-12-24(15)18-21-22-19(28-18)25-13-6-8-16(25)26/h15H,3-14H2,1-2H3,(H,20,27)/t15-/m0/s1

InChI Key

OYSCHYCACJFGEY-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD15008796

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.055

Distribution Coefficient, logD

0.303

Water Solubility, LogSw

-2.36

Polar Surface Area

72.146

Acid Dissociation Constant (pKa)

13.42

Base Dissociation Constant (pKb)

9.14

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

78.95

G397-0171 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G397-0171 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G397-0171?
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What is the minimum amount of G397-0171 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G397-0171
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G397-0171
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G397-0171 available by request