G397-0437 Screening compound: N-[2-(dimethylamino)ethyl]-N-[(furan-2-yl)methyl]-2-{methyl[5-(2-oxopyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}acetamide

G397-0437 Screening compound: N-[2-(dimethylamino)ethyl]-N-[(furan-2-yl)methyl]-2-{methyl[5-(2-oxopyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}acetamide
G397-0437 Screening compound: N-[2-(dimethylamino)ethyl]-N-[(furan-2-yl)methyl]-2-{methyl[5-(2-oxopyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G397-0437
N-[2-(dimethylamino)ethyl]-N-[(furan-2-yl)methyl]-2-{methyl[5-(2-oxopyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G397-0437

Molecular Formula

C18H26N6O3S (C18 H26 N6 O3 S)

Compound Name

N-[2-(dimethylamino)ethyl]-N-[(furan-2-yl)methyl]-2-{methyl[5-(2-oxopyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}acetamide

IUPAC name

N-[2-(dimethylamino)ethyl]-N-[(furan-2-yl)methyl]-2-{methyl[5-(2-oxopyrrolidin-1-yl)-134-thiadiazol-2-yl]amino}acetamide

SMILES

CN(C)CCN(Cc1ccco1)C(CN(C)c1nnc(N(CCC2)C2=O)s1)=O

InChI

InChI=1S/C18H26N6O3S/c1-21(2)9-10-23(12-14-6-5-11-27-14)16(26)13-22(3)17-19-20-18(28-17)24-8-4-7-15(24)25/h5-6,11H,4,7-10,12-13H2,1-3H3

InChI Key

MXOAEBMDYSEFFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15008850

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.161

Distribution Coefficient, logD

0.182

Water Solubility, LogSw

-2.04

Polar Surface Area

70.692

Acid Dissociation Constant (pKa)

15.59

Base Dissociation Constant (pKb)

8.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

G397-0437 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G397-0437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G397-0437?
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What is the minimum amount of G397-0437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G397-0437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G397-0437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G397-0437 available by request