G404-1729 Screening compound: 1-{1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]piperidine-4-carbonyl}-4-(4-methoxyphenyl)piperazine

G404-1729 Screening compound: 1-{1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]piperidine-4-carbonyl}-4-(4-methoxyphenyl)piperazine
G404-1729 Screening compound: 1-{1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]piperidine-4-carbonyl}-4-(4-methoxyphenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G404-1729
1-{1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]piperidine-4-carbonyl}-4-(4-methoxyphenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G404-1729

Molecular Formula

C22H31N5O4S (C22 H31 N5 O4 S)

Compound Name

1-{1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]piperidine-4-carbonyl}-4-(4-methoxyphenyl)piperazine

IUPAC name

1-{1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]piperidine-4-carbonyl}-4-(4-methoxyphenyl)piperazine

SMILES

CCn1cnc(S(N(CC2)CCC2C(N(CC2)CCN2c(cc2)ccc2OC)=O)(=O)=O)c1

InChI

InChI=1S/C22H31N5O4S/c1-3-24-16-21(23-17-24)32(29,30)27-10-8-18(9-11-27)22(28)26-14-12-25(13-15-26)19-4-6-20(31-2)7-5-19/h4-7,16-18H,3,8-15H2,1-2H3

InChI Key

QZEMKGVEHGPZAD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27138919

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.797

Distribution Coefficient, logD

1.796

Water Solubility, LogSw

-2.36

Polar Surface Area

71.236

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

4.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.50

G404-1729 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G404-1729 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G404-1729?
Check Price and Availability of G404-1729, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G404-1729 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G404-1729
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G404-1729
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G404-1729 available by request