G404-2233 Screening compound: N-[(4-ethoxy-3-methoxyphenyl)methyl]-1-{[1-(propan-2-yl)-1H-imidazol-4-yl]sulfonyl}piperidine-4-carboxamide

G404-2233 Screening compound: N-[(4-ethoxy-3-methoxyphenyl)methyl]-1-{[1-(propan-2-yl)-1H-imidazol-4-yl]sulfonyl}piperidine-4-carboxamide
G404-2233 Screening compound: N-[(4-ethoxy-3-methoxyphenyl)methyl]-1-{[1-(propan-2-yl)-1H-imidazol-4-yl]sulfonyl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G404-2233
N-[(4-ethoxy-3-methoxyphenyl)methyl]-1-{[1-(propan-2-yl)-1H-imidazol-4-yl]sulfonyl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G404-2233

Molecular Formula

C22H32N4O5S (C22 H32 N4 O5 S)

Compound Name

N-[(4-ethoxy-3-methoxyphenyl)methyl]-1-{[1-(propan-2-yl)-1H-imidazol-4-yl]sulfonyl}piperidine-4-carboxamide

IUPAC name

N-[(4-ethoxy-3-methoxyphenyl)methyl]-1-{[1-(propan-2-yl)-1H-imidazol-4-yl]sulfonyl}piperidine-4-carboxamide

SMILES

CCOc(ccc(CNC(C(CC1)CCN1S(c1cn(C(C)C)cn1)(=O)=O)=O)c1)c1OC

InChI

InChI=1S/C22H32N4O5S/c1-5-31-19-7-6-17(12-20(19)30-4)13-23-22(27)18-8-10-26(11-9-18)32(28,29)21-14-25(15-24-21)16(2)3/h6-7,12,14-16,18H,5,8-11,13H2,1-4H3,(H,23,27)

InChI Key

ORRDVXJGJBLEGP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27139048

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.569

Distribution Coefficient, logD

1.569

Water Solubility, LogSw

-2.51

Polar Surface Area

83.820

Acid Dissociation Constant (pKa)

14.07

Base Dissociation Constant (pKb)

1.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.50

G404-2233 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G404-2233 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G404-2233?
Check Price and Availability of G404-2233, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G404-2233 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G404-2233
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G404-2233
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G404-2233 available by request