G406-2474 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-{6-[(2-methylpiperidin-1-yl)sulfonyl]-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl}acetamide

G406-2474 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-{6-[(2-methylpiperidin-1-yl)sulfonyl]-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl}acetamide
G406-2474 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-{6-[(2-methylpiperidin-1-yl)sulfonyl]-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G406-2474
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-{6-[(2-methylpiperidin-1-yl)sulfonyl]-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G406-2474

Molecular Formula

C25H29N3O6S (C25 H29 N3 O6 S)

Compound Name

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-{6-[(2-methylpiperidin-1-yl)sulfonyl]-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl}acetamide

IUPAC name

N-(23-dihydro-14-benzodioxin-6-yl)-2-{6-[(2-methylpiperidin-1-yl)sulfonyl]-2-oxo-1234-tetrahydroquinolin-1-yl}acetamide

SMILES

CC(CCCC1)N1S(c(cc1)cc(CC2)c1N(CC(Nc(cc1)cc3c1OCCO3)=O)C2=O)(=O)=O

InChI

InChI=1S/C25H29N3O6S/c1-17-4-2-3-11-28(17)35(31,32)20-7-8-21-18(14-20)5-10-25(30)27(21)16-24(29)26-19-6-9-22-23(15-19)34-13-12-33-22/h6-9,14-15,17H,2-5,10-13,16H2,1H3,(H,26,29)/t17-/m0/s1

InChI Key

DOAIEEUETJTCKK-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27139418

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.59

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.695

Distribution Coefficient, logD

2.695

Water Solubility, LogSw

-3.32

Polar Surface Area

86.364

Acid Dissociation Constant (pKa)

11.21

Base Dissociation Constant (pKb)

2.98

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

G406-2474 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G406-2474 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G406-2474?
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What is the minimum amount of G406-2474 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G406-2474
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G406-2474
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G406-2474 available by request