G411-0144 Screening compound: N-[2-oxo-4-(pyrrolidin-1-yl)-2H-chromen-3-yl]cyclopropanecarboxamide

G411-0144 Screening compound: N-[2-oxo-4-(pyrrolidin-1-yl)-2H-chromen-3-yl]cyclopropanecarboxamide
G411-0144 Screening compound: N-[2-oxo-4-(pyrrolidin-1-yl)-2H-chromen-3-yl]cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G411-0144
N-[2-oxo-4-(pyrrolidin-1-yl)-2H-chromen-3-yl]cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G411-0144

Molecular Formula

C17H18N2O3 (C17 H18 N2 O3)

Compound Name

N-[2-oxo-4-(pyrrolidin-1-yl)-2H-chromen-3-yl]cyclopropanecarboxamide

IUPAC name

N-[2-oxo-4-(pyrrolidin-1-yl)-2H-chromen-3-yl]cyclopropanecarboxamide

SMILES

O=C(C1CC1)NC(C(Oc1c2cccc1)=O)=C2N1CCCC1

InChI

InChI=1S/C17H18N2O3/c20-16(11-7-8-11)18-14-15(19-9-3-4-10-19)12-5-1-2-6-13(12)22-17(14)21/h1-2,5-6,11H,3-4,7-10H2,(H,18,20)

InChI Key

KECBSXJEZRUQAQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27139727

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

298.34

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.531

Distribution Coefficient, logD

2.112

Water Solubility, LogSw

-3.18

Polar Surface Area

48.710

Acid Dissociation Constant (pKa)

8.05

Base Dissociation Constant (pKb)

-1.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.20

G411-0144 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G411-0144 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G411-0144?
Check Price and Availability of G411-0144, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G411-0144 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G411-0144
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G411-0144
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G411-0144 available by request