G414-0208 Screening compound: N4-(2,4-dimethylphenyl)-1-methyl-N6-[(4-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

G414-0208 Screening compound: N4-(2,4-dimethylphenyl)-1-methyl-N6-[(4-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
G414-0208 Screening compound: N4-(2,4-dimethylphenyl)-1-methyl-N6-[(4-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound G414-0208
N4-(2,4-dimethylphenyl)-1-methyl-N6-[(4-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G414-0208

Molecular Formula

C22H24N6 (C22 H24 N6)

Compound Name

N4-(2,4-dimethylphenyl)-1-methyl-N6-[(4-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

IUPAC name

N4-(24-dimethylphenyl)-1-methyl-N6-[(4-methylphenyl)methyl]-1H-pyrazolo[34-d]pyrimidine-46-diamine

SMILES

Cc1ccc(CNc2nc(Nc3c(C)cc(C)cc3)c(cnn3C)c3n2)cc1

InChI

InChI=1S/C22H24N6/c1-14-5-8-17(9-6-14)12-23-22-26-20(18-13-24-28(4)21(18)27-22)25-19-10-7-15(2)11-16(19)3/h5-11,13H,12H2,1-4H3,(H2,23,25,26,27)

InChI Key

VQOQECLGDUXRTO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27139834

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.47

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.056

Distribution Coefficient, logD

5.032

Water Solubility, LogSw

-4.49

Polar Surface Area

53.881

Acid Dissociation Constant (pKa)

17.14

Base Dissociation Constant (pKb)

6.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

G414-0208 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G414-0208 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G414-0208?
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What is the minimum amount of G414-0208 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G414-0208
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G414-0208
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G414-0208 available by request