G414-0280 Screening compound: 6-(4-cyclohexylpiperazin-1-yl)-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

G414-0280 Screening compound: 6-(4-cyclohexylpiperazin-1-yl)-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
G414-0280 Screening compound: 6-(4-cyclohexylpiperazin-1-yl)-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G414-0280
6-(4-cyclohexylpiperazin-1-yl)-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G414-0280

Molecular Formula

C23H31N7O (C23 H31 N7 O)

Compound Name

6-(4-cyclohexylpiperazin-1-yl)-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

IUPAC name

6-(4-cyclohexylpiperazin-1-yl)-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[34-d]pyrimidin-4-amine

SMILES

Cn1ncc2c1nc(N(CC1)CCN1C1CCCCC1)nc2Nc(cc1)ccc1OC

InChI

InChI=1S/C23H31N7O/c1-28-22-20(16-24-28)21(25-17-8-10-19(31-2)11-9-17)26-23(27-22)30-14-12-29(13-15-30)18-6-4-3-5-7-18/h8-11,16,18H,3-7,12-15H2,1-2H3,(H,25,26,27)

InChI Key

CBLLWVMHXRXNID-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27139844

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.531

Distribution Coefficient, logD

3.875

Water Solubility, LogSw

-4.09

Polar Surface Area

56.227

Acid Dissociation Constant (pKa)

16.38

Base Dissociation Constant (pKb)

7.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

G414-0280 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G414-0280 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G414-0280?
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What is the minimum amount of G414-0280 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G414-0280
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G414-0280
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G414-0280 available by request