G414-0289 Screening compound: 6-{[1,4'-bipiperidin]-1'-yl}-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

G414-0289 Screening compound: 6-{[1,4'-bipiperidin]-1'-yl}-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
G414-0289 Screening compound: 6-{[1,4'-bipiperidin]-1'-yl}-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G414-0289
6-{[1,4'-bipiperidin]-1'-yl}-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G414-0289

Molecular Formula

C23H31N7O (C23 H31 N7 O)

Compound Name

6-{[1,4'-bipiperidin]-1'-yl}-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

IUPAC name

6-{[14'-bipiperidin]-1'-yl}-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[34-d]pyrimidin-4-amine

SMILES

Cn1ncc2c1nc(N(CC1)CCC1N1CCCCC1)nc2Nc(cc1)ccc1OC

InChI

InChI=1S/C23H31N7O/c1-28-22-20(16-24-28)21(25-17-6-8-19(31-2)9-7-17)26-23(27-22)30-14-10-18(11-15-30)29-12-4-3-5-13-29/h6-9,16,18H,3-5,10-15H2,1-2H3,(H,25,26,27)

InChI Key

DXURBCRRXMKWQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27139847

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.222

Distribution Coefficient, logD

1.530

Water Solubility, LogSw

-4.08

Polar Surface Area

56.227

Acid Dissociation Constant (pKa)

16.38

Base Dissociation Constant (pKb)

10.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

G414-0289 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G414-0289 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G414-0289?
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What is the minimum amount of G414-0289 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G414-0289
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G414-0289
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G414-0289 available by request