G414-1360 Screening compound: 1-methyl-N6-propyl-N4-[2-(thiophen-2-yl)ethyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

G414-1360 Screening compound: 1-methyl-N6-propyl-N4-[2-(thiophen-2-yl)ethyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
G414-1360 Screening compound: 1-methyl-N6-propyl-N4-[2-(thiophen-2-yl)ethyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound G414-1360
1-methyl-N6-propyl-N4-[2-(thiophen-2-yl)ethyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G414-1360

Molecular Formula

C15H20N6S (C15 H20 N6 S)

Compound Name

1-methyl-N6-propyl-N4-[2-(thiophen-2-yl)ethyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

IUPAC name

1-methyl-N6-propyl-N4-[2-(thiophen-2-yl)ethyl]-1H-pyrazolo[34-d]pyrimidine-46-diamine

SMILES

CCCNc1nc(n(C)nc2)c2c(NCCc2cccs2)n1

InChI

InChI=1S/C15H20N6S/c1-3-7-17-15-19-13(12-10-18-21(2)14(12)20-15)16-8-6-11-5-4-9-22-11/h4-5,9-10H,3,6-8H2,1-2H3,(H2,16,17,19,20)

InChI Key

SGWKWFMEQKJJLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15010553

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

316.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.181

Distribution Coefficient, logD

3.122

Water Solubility, LogSw

-3.01

Polar Surface Area

56.874

Acid Dissociation Constant (pKa)

17.08

Base Dissociation Constant (pKb)

6.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

G414-1360 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G414-1360 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G414-1360?
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What is the minimum amount of G414-1360 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G414-1360
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G414-1360
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G414-1360 available by request