G414-1553 Screening compound: N6-(2-methoxyethyl)-1-methyl-N4-[(2-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

G414-1553 Screening compound: N6-(2-methoxyethyl)-1-methyl-N4-[(2-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
G414-1553 Screening compound: N6-(2-methoxyethyl)-1-methyl-N4-[(2-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound G414-1553
N6-(2-methoxyethyl)-1-methyl-N4-[(2-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G414-1553

Molecular Formula

C17H22N6O (C17 H22 N6 O)

Compound Name

N6-(2-methoxyethyl)-1-methyl-N4-[(2-methylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

IUPAC name

N6-(2-methoxyethyl)-1-methyl-N4-[(2-methylphenyl)methyl]-1H-pyrazolo[34-d]pyrimidine-46-diamine

SMILES

Cc1c(CNc2c(cnn3C)c3nc(NCCOC)n2)cccc1

InChI

InChI=1S/C17H22N6O/c1-12-6-4-5-7-13(12)10-19-15-14-11-20-23(2)16(14)22-17(21-15)18-8-9-24-3/h4-7,11H,8-10H2,1-3H3,(H2,18,19,21,22)

InChI Key

UOPJMHADPMAPGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140130

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

326.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.020

Distribution Coefficient, logD

2.968

Water Solubility, LogSw

-2.93

Polar Surface Area

64.357

Acid Dissociation Constant (pKa)

14.87

Base Dissociation Constant (pKb)

6.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.30

G414-1553 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G414-1553 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G414-1553?
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What is the minimum amount of G414-1553 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G414-1553
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G414-1553
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G414-1553 available by request