G414-1618 Screening compound: 1-methyl-N-[(3-methylphenyl)methyl]-6-(4-propylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

G414-1618 Screening compound: 1-methyl-N-[(3-methylphenyl)methyl]-6-(4-propylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
G414-1618 Screening compound: 1-methyl-N-[(3-methylphenyl)methyl]-6-(4-propylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G414-1618
1-methyl-N-[(3-methylphenyl)methyl]-6-(4-propylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G414-1618

Molecular Formula

C21H29N7 (C21 H29 N7)

Compound Name

1-methyl-N-[(3-methylphenyl)methyl]-6-(4-propylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

IUPAC name

1-methyl-N-[(3-methylphenyl)methyl]-6-(4-propylpiperazin-1-yl)-1H-pyrazolo[34-d]pyrimidin-4-amine

SMILES

CCCN(CC1)CCN1c1nc(NCc2cc(C)ccc2)c(cnn2C)c2n1

InChI

InChI=1S/C21H29N7/c1-4-8-27-9-11-28(12-10-27)21-24-19(18-15-23-26(3)20(18)25-21)22-14-17-7-5-6-16(2)13-17/h5-7,13,15H,4,8-12,14H2,1-3H3,(H,22,24,25)

InChI Key

YBQWCMSDQRDGCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140153

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

379.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.780

Distribution Coefficient, logD

3.076

Water Solubility, LogSw

-3.74

Polar Surface Area

50.702

Acid Dissociation Constant (pKa)

15.03

Base Dissociation Constant (pKb)

8.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

G414-1618 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G414-1618 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G414-1618?
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What is the minimum amount of G414-1618 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G414-1618
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G414-1618
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G414-1618 available by request