G416-3769 Screening compound: N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-N,4-dimethylbenzene-1-sulfonamide

G416-3769 Screening compound: N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-N,4-dimethylbenzene-1-sulfonamide
G416-3769 Screening compound: N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-N,4-dimethylbenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G416-3769
N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-N,4-dimethylbenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G416-3769

Molecular Formula

C25H28N4O3S (C25 H28 N4 O3 S)

Compound Name

N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-N,4-dimethylbenzene-1-sulfonamide

IUPAC name

N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-N4-dimethylbenzene-1-sulfonamide

SMILES

Cc(cc1)ccc1S(N(C)c1cncc(C(N2CCN(Cc3ccccc3)CC2)=O)c1)(=O)=O

InChI

InChI=1S/C25H28N4O3S/c1-20-8-10-24(11-9-20)33(31,32)27(2)23-16-22(17-26-18-23)25(30)29-14-12-28(13-15-29)19-21-6-4-3-5-7-21/h3-11,16-18H,12-15,19H2,1-2H3

InChI Key

OEQHNKZGZHZAQX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140218

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.209

Distribution Coefficient, logD

3.194

Water Solubility, LogSw

-3.26

Polar Surface Area

62.856

Acid Dissociation Constant (pKa)

28.02

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

G416-3769 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G416-3769 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G416-3769?
Check Price and Availability of G416-3769, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G416-3769 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G416-3769
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G416-3769
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G416-3769 available by request